Dr. Hiesberger earned his law degree from SMU School of Law where he focused on patent & trade secret law, licensing, as well as FDA-Regulations, and Investigations by the International Trade Commission. Dr. Hiesberger also holds a doctorate degree from the University of Vienna, related to nanotechnology and molecular biology, as well as an engineering degree in agricultural technology. His broad technical background and professional interest ranges from biological and medical inventions to nanotechnology, aviation, and agriculture.
Practice Emphasis
International and National Patent Procurement, Patentability, Technology Evaluations, Licensing, and Opinions related to the following:
- Biology
- Microbiology
- Genetics
- Protein & DNA-Biochemistry
- Molecular Interactions
- Molecular Signaling
- Transgenic Organisms
- Medical Technology
- Drugs
- Medical Devices
- Immunology
- Biologics
- Vaccines
- Dietary Supplements
- Nanotechnology
- Agricultural Technology
- Plant Biology
- Transgenic Animals
Training Before joining Chalker Flores, LLP, Dr. Hiesberger worked on intellectual property-related matters at academic and corporate institutions as well as law firms. Prior to becoming a lawyer, Dr. Hiesberger served as Assistant Professor of Internal Medicine at UT Southwestern and was Staff Scientist in the Department of Molecular Genetics, headed by the Nobel Laureates Michael Brown and Joseph Goldstein. He also served as Corporal in the Telecommunication Intelligence Unit, Central Command, Austria and has a U.S. Pilot License. Professional Affiliations - Member, State Bar of Texas
- Admitted to practice before United States Patent and Trademark Office
- Member, Dallas Bar Association
- Member, American Bar Association
- Texas Kidney Award (2003)
Administered by the Polycystic Kidney Foundation - Erwin-Schroedinger (1997)
Administered by the Austrian Science Fund - Nycomed Award (1996)
Administered by the Austrian Atherosclerosis Society
Proficiencies Bilingual in German & English Publications T. Hiesberger, Defining a “sale for importation”—statute and case law, ITCTLA Rep. (SA ed.) 53-60 (2009).
Y. Gong, Z. Ma, V. Patel, E. Fischer, T. Hiesberger, M. Pontoglio & P. Igarashi, HNF-1beta regulates transcription of the PKD modifier gene Kif12, 20 J. Am. Soc. Nephrol. 41-47 (2009). Z. Ma, Y. Gong, V. Patel, C. M. Karner, E. Fischer, T. Hiesberger, T. J. Carroll, M. Pontoglio & P. Igarashi, Mutations of HNF-1 beta inhibit epithelial morphogenesis through dysregulation of SOCS-3, 104 PNAS 20386-91 (2007).
T. Hiesberger & P. Igarashi, Elucidating the function of primary cilia by conditional gene inactivation, 14(4) Cur. Op. in Nephrol. Hyperten. 373-77 (2005).
T. Hiesberger, X. Shao, E. Gourley, A. Reimann, M. Pontoglio & P. Igarashi, Role of the HNF-1beta C-terminal domain in Pkhd1 gene transcription and renal cystogenesis, 280 J. Biol. Chem. 10578-86 (2005).
T. Hiesberger, Y. Bai, X. Shao, B. McNally, A. Sinclair, X. Tian, S. Somlo & P. Igarashi, Mutation of HNF-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice, 113 J. Clin. Invest. 814-25 (2004).
S. Guenette, Y. Chang, T. Hiesberger, J. A. Richardson, C. B. Eckman, E. A. Eckman, R. E. Hammer & J. Herz, Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development, 25 EMBO 420-31 (2006).
F. Lin, T. Hiesberger, K. Cordes, A. Sinclair, L. Goldstein, S. Somlo & P. Igarashi, Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease, 100 Proc. Natl. Acad. Sci. 5286-91 (2003).
T. Hiesberger, M. Trommsdorff, B. Howell, A. Goffinet, M. Mumby, J. Coope & J. Herz, Direct binding of Reelin to VLDL receptor and ApoE receptor-2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation, 24 Neuron 481-89 (1999).
M. Trommsdorff, M. Gotthardt, T. Hiesberger, J. Shelton, W. Stockinger, J. Nimpf, R. Hammer, J. Richardson & J. Herz, Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor-2, 97 Cell 689-701(1999).
T. Hiesberger, S. Huttler, A. Rohlmann, W. Schneider, K. Sandhoff & J. Herz, Cellular uptake of saposin precursor and lysosomal delivery by the low-density lipoprotein receptor-related protein. 17 EMBO 4617-25 (1998).
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